SLITRK4 anticorps (PE)

N° du produit ABIN1429020

Cet anticorps anti-SLITRK4 est un anticorps Lapin Polyclonal détectant SLITRK4 dans FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SLITRK4 anticorps (PE) (ABIN1429020)

Antigène: SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLITRK4 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-SLITRK4 anticorps (PE)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLITRK4

Isotype: IgG

Information d'application

Indications d'application: FCM(1:20-100)

Commentaires:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4°C

Date de péremption: 12 months

Détails sur SLITRK4

Antigène: SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))

Autre désignation: Slitrk4

Sujet:

SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK4 (SLIT and NTRK-like protein 4) is a 837 amino acid single-pass type I membrane protein that contains 18 LRR (leucine-rich) repeats and is expressed in neural tissues, specifically in the thalamus, hypothalamus, subventricular zone, CA3 region of the hippocampus and cortical plate. SLITRK4 may be upregulated in some astrocytic brain tumors such as glioblastomas, astrocytomas and primitive neuroectodermal tumors. As compared with its family member SLITRK2, SLITRK4 only weakly suppresses neurite outgrowth. A study using genome-wide transcriptional profiling suggested that the gene encoding SLITRK4, as well as the ARL5B and PLA2G7 genes, may be involved in the pathogenesis of preeclampsia.

Subcellular location: Extracellular

Synonyms: DKFZp547M2010, SLIK4_HUMAN, SLIT and NTRK like family member 4, SLIT and NTRK like protein 4, SLIT and NTRK-like protein 4, Slit and trk like 4 protein, Slit and trk like gene 4, SLITRK 4, SLITRK4.